The PCOS Brief · Free weekly newsletter

One PCOS study, explained in plain English. Every week.

What was studied, what it found, and what's actually actionable. Written by a public-health researcher (MPH, Columbia) who reads the research so you don't have to. ~4 minutes, no spam.

FREE · UNSUBSCRIBE ANYTIME BY ALISHAH KHAN, MPH · COLUMBIA
A muted editorial cover: 'The Mediterranean diet & testosterone' — a study of 224 women with PCOS linking olive oil, fish, legumes, and nuts to lower testosterone. Clay-blue, sage, and rose palette with an olive branch and a bowl motif.
June 23, 2026 4 min read
Does the Mediterranean diet lower testosterone in PCOS? What a study of 224 women found

Women who closely followed the Mediterranean diet, eating more olive oil, fish, legumes, and nuts, had lower testosterone, even after accounting for body weight, in a study of 224 women with PCOS.

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Why the Brief exists

PCOS is a lot and very little at the same time. The research exists. It just rarely reaches you.

1 in 10 women have PCOS, and the 2023 international guideline names lifestyle as first-line care. The Brief reads the studies behind that for you: one a week, in plain English.

Citation: Teede HJ et al., 2023 International Evidence-based PCOS Guideline. Human Reproduction, 2023.

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Sound familiar?

From the women we asked.

We surveyed 113 women with PCOS and ran 35 user research conversations about what wasn't working. The same answers came up over and over.

Every app just asks if I'm pregnant.
They assume 28-day cycles and have never heard of hirsutism, even though it affects 70–80% of women with PCOS.
It feels overwhelming trying to keep track of all the things my body is doing.
Too many fields, too many apps, too many reminders for things that don't even apply to you.
I thought tracking would make my doctor take me more seriously.
Fifteen-minute appointments. No clear timeline of when things started or what changed.
Preset symptoms don't really match, and it's hard to add my own.
Generic symptom lists miss what matters for PCOS. Without the right variables, you can't tell if anything is working.
We're also building the app

Sachi for iOS: PCOS-aware tracking, coming to the App Store.

01

Make it yours. Turn on only the symptoms, meds, and supplements you care about.

02

Check in daily. Swipe through your cards and daily goals. Apple Health can fill in steps, sleep, and weight automatically.

03

See what changes. Walk into your next appointment with real data, not vague memory.

Also in the app: wellness programs inspired by peer-reviewed research, with daily nutrition, movement, sleep, and mindfulness goals. Sachi doesn't diagnose, treat, or prevent anything. It can surface studies about supplements, but it never tells you what to take. Those decisions stay between you and your provider.

iOS · LAUNCHING SOON · NOT MEDICAL ADVICE
Daily check-in screen in the Sachi app
Dashboard screen in the Sachi app
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Why we're building this

Two women co-founders, building the tool we kept being asked for.

We met at Columbia. After 35 user research conversations and a 113-person survey, we kept hearing the same thing: the research on lifestyle interventions exists, but no tool helps women who self-manage their PCOS actually use it.

Co-founder · CEO

Daniella Tincani Ueki

COLUMBIA MBA · EX-MCKINSEY

I started Sachi at Columbia Business School after surveying 113 women with PCOS and interviewing the doctors who treat them. I'm building what I kept hearing should already exist.

Co-founder · Clinical & Research

Alishah Khan, MPH

COLUMBIA MAILMAN MPH · WRITES THE PCOS BRIEF

I'm a public-health researcher trained at Columbia's Mailman School. I make sure every variable Sachi tracks maps to peer-reviewed PCOS research, and I write the Brief every week.

Quick answers.

Does Sachi diagnose or treat PCOS?

No. Sachi is a tracking and wellness tool. It doesn't diagnose, treat, or prevent any condition, and its programs are wellness content inspired by peer-reviewed research, not treatment plans.

Is this medical advice?

No. The Brief and the app share wellness insights inspired by peer-reviewed research. Discuss any changes with your healthcare provider.

What does it cost?

The Brief is free, every week. App pricing will be announced at launch.

Android?

iOS first. Subscribe to the Brief and you'll be the first to know when Android lands.

What about my privacy?

This site never collects health data, only your email if you give it. Read the privacy policy →